Histidine, an essential amino acid that our bodies cannot synthesize independently, is vital for skin health and must be obtained through dietary sources or supplements. It possesses antioxidant and anti-inflammatory properties, pivotal for preserving skin integrity. By scavenging free radicals, histidine mitigates oxidative stress, shielding skin cells from damage. Furthermore, it regulates inflammatory responses, aiding in maintaining a healthy skin barrier. Histidine plays a crucial role in balancing skin pH, which is imperative for optimal barrier function. Additionally, it contributes to skin hydration by supporting the production of natural moisturizing factors (NMFs) like urea and pyrrolidone carboxylic acid. This promotes adequate moisture retention, fostering a hydrated and resilient complexion.